... the nonspatial version of the task. This study confirms and extends to more specific
aspects of memory our earlier finding that age-related cognitive deterioration in rats
was antagonized by life-long calorie restriction. Keywords. ...

... 101 no. 45; > Blanka Rogina , 15998–16003. Sir2 mediates longevity in the fly through a pathway
related to calorie restriction. ... Next Section. Abstract. Calorie restriction can extend life span in
a variety of species including mammals, flies, nematodes, and yeast. ...

... Report. Calorie Restriction Promotes Mitochondrial Biogenesis by Inducing the
Expression of eNOS. ... Abstract. Calorie restriction extends life span in organisms ranging
from yeast to mammals. Here, we report that calorie restriction ...

Background: Calorie restriction increases longevity in many organisms, and calorie
restriction or its mimetic might increase longevity in humans. It is unclear if calorie
restriction/dieting contributes to cognitive impairment. During this randomized controlled ...

Abstract Controversy exists as to whether lifelong 40% calorie restriction (CR) enhances,
has no effect on, or disrupts cognitive function during aging. Here, we report the effects of
CR versus ad-lib feeding on cognitive function in male Brown Norway× Fisher344 rats ...

... Calorie restriction and neurons. In addition to ... stroke 21 . CR has also been reported
to stimulate neurogenesis and enhance synaptic plasticity, which might increase
the ability of the brain to resist cognitive decline 21 . Some ...

... Go to PNAS Homepage; > Current Issue; > vol. 101 no. 17; > Luigi Fontana , 6659–6663.
Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. ...

... 103 no. 6; > G. López-Lluch , 1768–1773. Calorie restriction induces mitochondrial biogenesis
and bioenergetic efficiency. ... Calorie restriction (CR) is the most robust, nongenetic intervention
that increases lifespan and reduces the rate of aging in a variety of species. ...