Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor

GC Brainard, JP Hanifin, JM Greeson… - Journal of …, 2001 - Soc Neuroscience
… during the study period, or had irregular sleeping schedules were excluded from this study.
The … Subjects who had a relatively stable daily sleeping pattern, passed a physical exam for …

[PDF][PDF] Ocular input for human melatonin regulation: relevance to breast cancer

G Glickman, R Levin, GC Brainard - Neuroendocrinology Letters, 2002 - instantdaylite.com
… and sleep by autonomic drugs. J Clin Endocrinol Metab 1976; 42:752–764. 32 Jimerson
DC, Lynch HJ, Post RM, Wurtman RJ, Bunney WE. Urinary melatonin rhythms during sleep

Breast cancer and circadian disruption from electric lighting in the modern world

RG Stevens, GC Brainard, DE Blask… - CA: a cancer journal …, 2014 - Wiley Online Library
… salient features are melatonin production, sleep, and the … in blind women, and the impact of
sleep duration on risk. If electric … They also reported that restricted sleep altered melatonin by …

Human melatonin regulation is not mediated by the three cone photopic visual system

GC Brainard, JP Hanifin, MD Rollag… - The Journal of …, 2001 - academic.oup.com
… on light-induced melatonin suppression. Healthy subjects with stable sleeping patterns (wake-up …
Plasma collected before and after exposures was quantified for melatonin. Subjects …

Adverse health effects of nighttime lighting: comments on American Medical Association policy statement

RG Stevens, GC Brainard, DE Blask… - American journal of …, 2013 - Elsevier
… , such as circulating melatonin, circadian gene expression, and sleep. The term circadian …
of sleep relative to the circadian clock, and/or the acute suppression of nocturnal melatonin

Meeting report: the role of environmental lighting and circadian disruption in cancer and other diseases

RG Stevens, DE Blask, GC Brainard… - Environmental …, 2007 - ehp.niehs.nih.gov
… other, impairing our ability to sleep and wake at the appropriate … , for example, in suppressing
melatonin synthesis or elevating … melatonin as an adjuvant therapy for light- or melatonin-…

Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humans

…, MD Rollag, JP Hanifin, GC Brainard - Journal of applied …, 2011 - journals.physiology.org
… Disturbed circadian rhythms and sleep loss have been … was developed for plasma melatonin
suppression in healthy subjects (n… light exposures and quantified for melatonin. The results …

Pupil size regulation of threshold of light-induced melatonin suppression

…, MD Rollag, GC Brainard - The Journal of Clinical …, 1993 - academic.oup.com
… Figure 2 illustrates the plasma melatonin change ratios on … suppress melatonin relative to
the normal rise of melatonin (free … 1991 The durations of human melatonin secretion and sleep

Randomized trial of polychromatic blue-enriched light for circadian phase shifting, melatonin suppression, and alerting responses

…, E Gerner, C Pineda, M Rollag, GC Brainard - Physiology & …, 2019 - Elsevier
… Following an 8 h recovery sleep, a second 30-h CR was performed. Melatonin suppression
… Phase-shifts were calculated from the clock time difference in dim light melatonin onset time …

Spectral responses of the human circadian system depend on the irradiance and duration of exposure to light

JJ Gooley, SMW Rajaratnam, GC Brainard… - Science translational …, 2010 - science.org
… in sensitivity for melatonin suppression in continuous light We measured melatonin suppression
… were scheduled to sleep and wake at their regular prestudy sleep-wake times (8 hours …