Abstract: This paper was aimed to synthesize a new group of 2-phenoxy [1, 2, 4] triazolo [1, 5-
a] quinazolin-5-one and their derivatives, then evaluate their antimicrobial activities.
Antibacterial activity of the target molecules was tested against a variety of species from

Abstract Background Several quinazoline and triazole derivatives are reported to possess a
wide-range of interesting pharmacological effects. Although various triazoloquinazoline
subclasses having been synthesized and studied, the preparation of 1, 2, 4-triazolo [1, 5-a]

Abstract The optimized molecular structure, vibrational frequencies, corresponding
vibrational assignments of 5-(adamantan-1-yl)-3-anilinomethyl-2, 3-dihydro-1, 3, 4-
oxadiazole-2-thione have been investigated experimentally and theoretically. The

Abstract: A series of 2-phenoxy-triazoloquinazoline derivatives have been evaluated against
herpes simplex viruses ie HSV-1 and HSV-2. The antiviral activity of the titled compounds
against HSV-1 and HSV-2 evaluated using Vero cells (derived from the kidney of a normal

Abstract A series of some newly methylsulfanyl-triazoloquinazoline derivatives (1–21) have
been tested against Coxsackievirus B4 and Adenovirus type 7. The antiviral activity of the
titled compounds against Coxsackie B4 and Adeno type 7 was evaluated in BGM and Hep-2

Abstract Series of 3-alkyl, 3-aryl-5, 5-diphenylimidazolidine-2, 4-diones (2–8) and 3-
phenacyl-5, 5-diphenylimidazolidine-2, 4-diones (9–20) were designed, synthesized, and
tested for their antitumor activity. The 13 compounds (3–8, 10–15 and 20) were selected by

Abstract: A new series of 2-amino-benzo [de] isoquinoline-1, 3-diones was synthesized and
fully characterized in our previous paper. Here, their cytotoxic effects have been evaluated in
vitro in relation to colon HCT-116, hepatocellular Hep-G2 and breast MCF-7 cancer cell

Abstract: As part of our search for new compounds having antiviral effects, the prepared 2-
aminonaphthalimide series was examined for its activity against the herpes simplex viruses
HSV-1 and HSV-2. This represents the first study of the antiviral effects of this class of

Abstract Houk and co-workers clarified several aspects of the mechanism of the Fischer
indole synthesis, showing that the SCS-MP2/6-31G (d)//MP2/6-31G (d) method is suitable for
studying the mechanism in water. Fluorine substitution can affect the kinetic and

Abstract Vibrational spectral analysis of 2-[(4-chlorobenzyl) sulfanyl]-4-(2-methylpropyl)-6-
(phenylsulfanyl)-pyrimidine-5-carbonitrile was carried out using FT-IR and FT-Raman
spectroscopic techniques. The equilibrium geometry and vibrational wave numbers have