Stigma is a social construction which dramatically affects the life experiences of the
individuals infected with the human immunodeficiency virus (HIV) and their partners, family
and friends. While it has been generally recognized that the nature of stigma varies across …

With the advent of thrombolytic therapy and other coronary reperfusion strategies, rapid
identification and treatment of acute myocardial infarction greatly reduces mortality.
Unfortunately, many patients delay seeking medical care and miss the benefits afforded by …

Activating mutations of the FLT3 gene occur because of an internal tandem duplication of
the juxta-membrane domain (FLT3/ITD) or point mutation of the activation loop domain
(FLT3/ALM). The presence of FLT3 mutations as well as the allelic ratio of FLT3/ITD (ITD-AR …

Although the use of weak electrical currents to stimulate the brain has been described for centuries
in the history of medicine, it has been reintroduced with higher intensity currents since 2000 as
'transcranial direct current stimulation' (tDCS).1 It involves passing a weak, depolarising current …

Translocations involving chromosome 11q23 frequently occur in pediatric AML and are
associated with poor prognosis. In most cases, the MLL-gene localized at 11q23 is involved,
and more than 50 translocation partners have been described. Clinical outcome data of the …

In this article we describe the development, analysis, and interpretation of a novel item
format we call Ordered Multiple-Choice (OMC). A unique feature of OMC items is that they
are linked to a model of student cognitive development for the construct being measured …

Learning progressions are ordered descriptions of students' understanding of a given
concept. In this paper, we describe the iterative process of developing a force and motion
learning progression and associated assessment items. We report on a pair of studies …

CCG-2961 incorporated 3 new agents, idarubicin, fludarabine and interleukin-2, into a
phase 3 AML trial using intensive-timing remission induction/consolidation and related
donor marrow transplantation or high-dose cytarabine intensifi-cation. Among 901 patients …

Purpose: Self‐management is a dynamic process in which individuals actively manage a
chronic illness. Self‐management models are limited in their specification of the processes
of self‐management. The purpose of this article is to delineate processes of self …