Arousal dissociates amygdala and hippocampal fear responses: evidence from simultaneous fMRI and skin conductance recording

…, ML Phillips, MJ Brammer, D Skerrett, J Lagopoulos… - Neuroimage, 2001 - Elsevier
The experience and appraisal of threat is essential to human and animal survival. Lesion
evidence suggests that the subjective experience of fear relies upon amygdala-medial
frontal activity (as well as autonomic arousal), whereas the factual context of threat stimuli …

[HTML][HTML] Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group

…, H Völzke, D Hoehn, M Czisch, J Lagopoulos… - Molecular …, 2016 - nature.com
The pattern of structural brain alterations associated with major depressive disorder (MDD)
remains unresolved. This is in part due to small sample sizes of neuroimaging studies
resulting in limited statistical power, disease heterogeneity and the complex interactions …

[HTML][HTML] The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

…, B Krńmer, JBJ Kwok, J Lagopoulos… - Brain imaging and …, 2014 - Springer
Abstract The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA)
Consortium is a collaborative network of researchers working together on a range of large-
scale studies that integrate data from 70 institutions worldwide. Organized into Working …

A double-blind, sham-controlled trial of transcranial direct current stimulation for the treatment of depression

…, A Alonzo, GS Malhi, J Lagopoulos… - International Journal …, 2010 - academic.oup.com
Two recent sham-controlled studies found that transcranial direct current stimulation (tDCS)
was an effective treatment for depression. As tDCS is painless, relatively safe and
inexpensive, its efficacy in treating depression warrants further investigation. This double …

Diffuse axonal injury in severe traumatic brain injury visualized using high-resolution diffusion tensor imaging

J Xu, IA Rasmussen, J Lagopoulos… - Journal of …, 2007 - liebertpub.com
Traumatic brain injury (TBI) is the most common cause of death and disability in young
people. The functional outcome in patients with TBI cannot be explained by focal pathology
alone, and diffuse axonal injury (DAI) is considered a major contributor to the neurocognitive …

Cognitive generation of affect in bipolar depression: an fMRI study

GS Malhi, J Lagopoulos, PB Ward… - European Journal of …, 2004 - Wiley Online Library
Individuals with bipolar disorder manifest the full spectrum of emotions ranging from
depression to mania. In attempting to understand the functional substrates of mood we
attempted to identify brain regions associated with the cognitive generation of affect in …

Increased theta and alpha EEG activity during nondirective meditation

J Lagopoulos, J Xu, I Rasmussen, A Vik… - The Journal of …, 2009 - liebertpub.com
Objectives: In recent years, there has been significant uptake of meditation and related
relaxation techniques, as a means of alleviating stress and maintaining good health. Despite
its popularity, little is known about the neural mechanisms by which meditation works, and …

A systematic review of resting-state functional-MRI studies in major depression

…, DF Hermens, IB Hickie, J Lagopoulos - Journal of affective …, 2012 - Elsevier
Background To evaluate the literature pertaining to the use of resting-state functional
magnetic resonance imaging (fMRI) in Major Depression (MD). Methods A search for papers
published in English was conducted using MedLine, Embase, PsycINFO, OvidSP, and …

An emotional Stroop functional MRI study of euthymic bipolar disorder

GS Malhi, J Lagopoulos, PS Sachdev… - Bipolar …, 2005 - Wiley Online Library
Objective: To identify the brain regions associated with emotional processing in euthymic
bipolar patients. Methods: The study examined 12 euthymic bipolar patients using functional
magnetic resonance imaging (fMRI) while performing an emotional Stroop (eStroop) task …

Is a lack of disgust something to fear? A functional magnetic resonance imaging facial emotion recognition study in euthymic bipolar disorder patients

GS Malhi, J Lagopoulos, PS Sachdev… - Bipolar …, 2007 - Wiley Online Library
Objectives: To determine the neural responses invoked in the recognition of facial fear and
disgust in euthymic bipolar patients as compared with healthy subjects. Methods: This study
examined 10 female euthymic bipolar patients, and 10 suitably matched healthy subjects …