We performed a meta-analysis of 14 genome-wide association studies of coronary artery
disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of
European descent followed by genotyping of top association signals in 56,682 additional …

Obesity results from the interaction of genetic and environmental factors. To search for
sequence variants that affect variation in two common measures of obesity, weight and body
mass index (BMI), both of which are highly heritable, we performed a genome-wide …

Background Platelet glycoprotein IIb/IIIa is a membrane receptor for fibrinogen and von
Willebrand factor, and it has an important role in platelet aggregation. It is known to be
involved in the pathogenesis of acute coronary syndromes. Previously, we found a high …

People want their social institutions to be procedurally efficient and fair, to enable the
realization of worthy collective and personal goals, to produce results which are just, and to
leave them free to pursue what ever activities they themselves choose. Most political …

To study endocardial wall motion and thickness as indexes of infarction, we used two-dimen-
sional echocardiography to examine regional percentages of systolic wall thickening (% Th)
and endocardial motion (% EM) in infarcted canine hearts. Thirteen dogs were studied 48 …

Adult human height is one of the classical complex human traits 1. We searched for
sequence variants that affect height by scanning the genomes of 25,174 Icelanders, 2,876
Dutch, 1,770 European Americans and 1,148 African Americans. We then combined these …