16S ribosomal DNA amplification for phylogenetic study.
WG Weisburg, SM Barns, DA Pelletier… - Journal of …, 1991 - Am Soc Microbiol
ABSTRACT A set of oligonucleotide primers capable of initiating enzymatic amplification
(polymerase chain reaction) on a phylogenetically and taxonomically wide range of bacteria
is described along with methods for their use and examples. One pair of primers is capable …
(polymerase chain reaction) on a phylogenetically and taxonomically wide range of bacteria
is described along with methods for their use and examples. One pair of primers is capable …
[CITATION][C] Using antibodies: a laboratory manual
E Harlow, D Lane, E Harlow - 1999 - Cold Spring Harbor Laboratory …
Surfing the p53 network
B Vogelstein, D Lane, AJ Levine - Nature, 2000 - nature.com
The p53 tumour-suppressor gene integrates numerous signals that control cell life and
death. As when a highly connected node in the Internet breaks down, the disruption of p53
has severe consequences. able confusion and controversy. Here we suggest that signalling …
death. As when a highly connected node in the Internet breaks down, the disruption of p53
has severe consequences. able confusion and controversy. Here we suggest that signalling …
Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on …
Background Contemporary clinical risk stratification schemata for predicting stroke and
thromboembolism (TE) in patients with atrial fibrillation (AF) are largely derived from risk
factors identified from trial cohorts. Thus, many potential risk factors have not been included …
thromboembolism (TE) in patients with atrial fibrillation (AF) are largely derived from risk
factors identified from trial cohorts. Thus, many potential risk factors have not been included …
T antigen is bound to a host protein in SY40-transformed cells
DP Lane, LV Crawford - Nature, 1979 - Springer
THE early region of the small DNA tumour virus, simian virus 40 (SV40), is known to code for
at least two polypeptides, the t and T antigens ('small t'and 'large T'). Both these polypeptides
are expressed in cells transformed by the virus 1–4 and the T antigen has been shown to be …
at least two polypeptides, the t and T antigens ('small t'and 'large T'). Both these polypeptides
are expressed in cells transformed by the virus 1–4 and the T antigen has been shown to be …
Rapid determination of 16S ribosomal RNA sequences for phylogenetic analyses
Although the applicability of small subunit ribosomal RNA (16S rRNA) sequences for
bacterial classification is now well accepted, the general use of these molecules has been
hindered by the technical difficulty of obtaining their sequences. A protocol is described for …
bacterial classification is now well accepted, the general use of these molecules has been
hindered by the technical difficulty of obtaining their sequences. A protocol is described for …
A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey
R Pisters, DA Lane, R Nieuwlaat, CB De Vos… - Chest, 2010 - Elsevier
Objective Despite extensive use of oral anticoagulation (OAC) in patients with atrial
fibrillation (AF) and the increased bleeding risk associated with such OAC use, no handy
quantification tool for assessing this risk exists. We aimed to develop a practical risk score to …
fibrillation (AF) and the increased bleeding risk associated with such OAC use, no handy
quantification tool for assessing this risk exists. We aimed to develop a practical risk score to …
[HTML][HTML] Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial
RT Chlebowski, SL Hendrix, RD Langer, ML Stefanick… - Jama, 2003 - jamanetwork.com
ContextThe Women's Health Initiative trial of combined estrogen plus progestin was stopped
early when overall health risks, including invasive breast cancer, exceeded benefits.
Outstanding issues not previously addressed include characteristics of breast cancers …
early when overall health risks, including invasive breast cancer, exceeded benefits.
Outstanding issues not previously addressed include characteristics of breast cancers …
Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some …
PA Hall, DA Levison, AL Woods, CCW Yu… - The Journal of …, 1990 - Wiley Online Library
Proliferating cell nuclear antigen (PCNA) is a 36 kD nuclear protein associated with the cell
cycle. A monoclonal antibody, PC10, that recognizes a fixation and processing resistant
epitope has been used to investigate its tissue distribution. Nuclear PCNA immunoreactivity …
cycle. A monoclonal antibody, PC10, that recognizes a fixation and processing resistant
epitope has been used to investigate its tissue distribution. Nuclear PCNA immunoreactivity …
p53 in health and disease
KH Vousden, DP Lane - Nature reviews Molecular cell biology, 2007 - nature.com
As a component of the response to acute stress, p53 has a well established role in
protecting against cancer development. However, it is now becoming clear that p53 can
have a much broader role and can contribute to the development, life expectancy and …
protecting against cancer development. However, it is now becoming clear that p53 can
have a much broader role and can contribute to the development, life expectancy and …
