Objective: Our objective was to update the guidelines for the evaluation and treatment of
androgen deficiency syndromes in adult men published previously in 2006. Participants:
The Task Force was composed of a chair, selected by the Clinical Guidelines Subcommittee …

Testosterone (T) therapy for hypogonadal men should correct the clinical abnormalities of T
deficiency, including improvement of sexual function, increase in muscle mass and strength,
and decrease in fat mass, with minimal adverse effects. We have shown that administration …

Objective: The objective was to provide guidelines for the evaluation and treatment of
androgen deficiency syndromes in adult men. Participants: The Task Force was composed
of a chair, selected by the Clinical Guidelines Subcommittee of The Endocrine Society, five …

Transdermal testosterone (T) delivery represents an effective alternative to injectable
androgens. We studied 163 hypogonadal men who applied 5, 7.5, or 10 g AndroGel (T gel)
1% CIII per day for up to 42 months. Efficacy data were presented in 123 subjects …

The diagnosis of male hypogonadism requires the demonstration of a low serum
testosterone (T) level. We examined serum T levels in pedigreed samples taken from 62
eugonadal and 60 hypogonadal males by four commonly used automated immunoassay …

The effect of testosterone (T) replacement on changes in mood was studied for 60 days in 51
hypogonadal men. All patients were withdrawn from their prior T replacement for at least 6
weeks before enrollment. Of these patients, 18 received T enanthate 200 mg im every 20 …

Programmed cell death is an evolutionarily conserved cell death process that plays a major
role during normal development and homeostasis. In many cases, the ordered execution of
this internal death programme leads to typical morphological and biochemical changes that …

Plasma levels of FSH, LH, progesterone (P), 17-hydroxy-progesterone (17-OHP), and
estradiol-17β (E2) were measured daily by radioimmunoassay in eleven menstrual cycles
from eleven normally menstruating women. The following criteria were used as indirect …

Transdermal delivery of testosterone (T) represents an effective alternative to injectable
androgens. Transdermal T patches normalize serum T levels and reverse the symptoms of
androgen deficiency in hypogonadal men. However, the acceptance of the closed system T …

Reproductive hormonal dynamics were assessed in 10 massively obese men, 200–380% of
ideal body weight (percentage ideal body weight) and 11 similarly-aged controls who were
85–135% of ideal body weight. The mean serum testosterone of the obese group was …