[HTML][HTML] Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients
CA Pierce, P Preston-Hurlburt, Y Dai… - Science translational …, 2020 - stm.sciencemag.org
Children and youth infected with severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) have milder disease than do adults, and even among those with the recently
described multisystem inflammatory syndrome, mortality is rare. The reasons for the
differences in clinical manifestations are unknown but suggest that age-dependent factors
may modulate the antiviral immune response. We compared cytokine, humoral, and cellular
immune responses in pediatric (children and youth, age< 24 years)(n= 65) and adult (n= 60) …
CoV-2) have milder disease than do adults, and even among those with the recently
described multisystem inflammatory syndrome, mortality is rare. The reasons for the
differences in clinical manifestations are unknown but suggest that age-dependent factors
may modulate the antiviral immune response. We compared cytokine, humoral, and cellular
immune responses in pediatric (children and youth, age< 24 years)(n= 65) and adult (n= 60) …
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