Analysis of one million base pairs of Neanderthal DNA
Neanderthals are the extinct hominid group most closely related to contemporary humans,
so their genome offers a unique opportunity to identify genetic changes specific to
anatomically fully modern humans. We have identified a 38,000-year-old Neanderthal fossil
that is exceptionally free of contamination from modern human DNA. Direct high-throughput
sequencing of a DNA extract from this fossil has thus far yielded over one million base pairs
of hominoid nuclear DNA sequences. Comparison with the human and chimpanzee …
so their genome offers a unique opportunity to identify genetic changes specific to
anatomically fully modern humans. We have identified a 38,000-year-old Neanderthal fossil
that is exceptionally free of contamination from modern human DNA. Direct high-throughput
sequencing of a DNA extract from this fossil has thus far yielded over one million base pairs
of hominoid nuclear DNA sequences. Comparison with the human and chimpanzee …
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