Abstract Each year the American Cancer Society estimates the numbers of new cancer
cases and deaths that will occur in the United States in the current year and compiles the
most recent data on cancer incidence, mortality, and survival. Incidence data were collected …

Each year, the American Cancer Society estimates the numbers of new cancer cases and
deaths that will occur in the United States in the current year and compiles the most recent
data on cancer incidence, mortality, and survival. Incidence data were collected by the …

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WordNet is an on-line lexical reference system whose design is inspired by current
psycholinguistic theories of human lexical memory. English nouns, verbs, and adjectives are
organized into synonym sets, each representing one underlying lexical concept. Different …

January 12–14, 2000), sponsored by the American Associa- tion of Pharmaceutical Scientists
and the US Food and Drug Administration. The bioanalytical method validation work- shop of
January 12–14, 2000 was directed towards small mol- ecules. A separate workshop was held …

Neural connections, providing the substrate for functional networks, exist whether or not they
are functionally active at any given moment. However, it is not known to what extent brain
regions are continuously interacting when the brain is “at rest.” In this work, we identify the …

Background In an open-label, randomized, phase 3 trial, we compared the efficacy and
safety of paclitaxel with that of paclitaxel plus bevacizumab, a monoclonal antibody against
vascular endothelial growth factor, as initial treatment for metastatic breast cancer. Methods …

Background Enzalutamide (formerly called MDV3100) targets multiple steps in the androgen-
receptor–signaling pathway, the major driver of prostate-cancer growth. We aimed to
evaluate whether enzalutamide prolongs survival in men with castration-resistant prostate …

Purpose.—To develop a guideline to improve the accuracy of immunohistochemical (IHC)
estrogen receptor (ER) and progesterone receptor (PgR) testing in breast cancer and the
utility of these receptors as predictive markers. Methods.—The American Society of Clinical …

We review Phanerozoic sea-level changes [543 million years ago (Ma) to the present] on
various time scales and present a new sea-level record for the past 100 million years (My).
Long-term sea level peaked at 100±50 meters during the Cretaceous, implying that ocean …