PCR amplification of the Irish potato famine pathogen from historic specimens

JB Ristaino, CT Groves, GR Parra - Nature, 2001 - nature.com
Late blight, caused by the oomycete plant pathogen Phytophthora infestans, is a devastating
disease of potato and was responsible for epidemics that led to the Irish potato famine in
1845 (refs 1, 2, 3, 4, 5). Before the 1980s, worldwide populations of P. infestans were
dominated by a single clonal lineage, the US-1 genotype or Ib mitochondrial DNA (mtDNA)
haplotype, and sexual reproduction was not documented outside Mexico, the centre of
diversity of the pathogen 6, 7. Here we describe the amplification and sequencing of 100 …
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