Dynamic DNA methylation programs persistent adverse effects of early-life stress

C Murgatroyd, AV Patchev, Y Wu, V Micale… - Nature …, 2009 - nature.com
Abstract Adverse early life events can induce long-lasting changes in physiology and
behavior. We found that early-life stress (ELS) in mice caused enduring hypersecretion of
corticosterone and alterations in passive stress coping and memory. This phenotype was ...

Symptoms, adverse effects, and complications associated with dobutamine stress echocardiography. Experience in 1118 patients.

H Mertes, SG Sawada, T Ryan, DS Segar, R Kovacs… - Circulation, 1993 - Am Heart Assoc
BACKGROUND The use of dobutamine stress echocardiography for the evaluation of
coronary artery disease is rapidly expanding. New applications of the technique are being
investigated in a wide variety of patients including those with advanced coronary artery ...

Effects of stress and social support on mothers and premature and full-term infants

KA Crnic, MT Greenberg, AS Ragozin, NM Robinson… - Child development, 1983 - JSTOR
... Additionally, social support moderated the adverse effects of stress on mother's life satisfaction
and on several behavioral ... as rated by the mothers on a five-point scale from very bad to very ...
probability that, with a young infant, families spend less time in out- side social activities ...

[HTML][HTML] Making a bad thing worse: adverse effects of stress on drug addiction

JN Cleck, JA Blendy - The Journal of clinical investigation, 2008 - Am Soc Clin Investig
Sustained exposure to various psychological stressors can exacerbate neuropsychiatric
disorders, including drug addiction. Addiction is a chronic brain disease in which individuals
cannot control their need for drugs, despite negative health and social consequences. The ...

Developmental changes in embryonic resistance to adverse effects of maternal heat stress in cows

AD Ealy, M Drost, PJ Hansen - Journal of Dairy Science, 1993 - Elsevier
Abstract The objective of this study was to determine whether bovine embryos become more
resistant to deleterious effects of maternal heat stress as early embryonic development
progresses. Superovulated, lactating Holstein cows were bred by AI and assigned to be ...

Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM 10)

K Donaldson, V Stone, PJA Borm, LA Jimenez… - Free Radical Biology …, 2003 - Elsevier
This review focuses on the potential role that oxidative stress plays in the adverse effects of
PM10. The central hypothesis is that the ability of PM10 to cause oxidative stress underlies
the association between increased exposure to PM10 and both exacerbations of lung ...

[HTML][HTML] Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress

YY Sautin, T Nakagawa, S Zharikov… - American Journal of …, 2007 - Am Physiological Soc
Abstract Uric acid is considered a major antioxidant in human blood that may protect against
aging and oxidative stress. Despite its proposed protective properties, elevated levels of uric
acid are commonly associated with increased risk for cardiovascular disease and mortality ...

The antidepressant agomelatine blocks the adverse effects of stress on memory and enables spatial learning to rapidly increase neural cell adhesion molecule ( …

L Conboy, C Tanrikut, PR Zoladz… - International …, 2009 - ijnp.oxfordjournals.org
Abstract Agomelatine, a novel antidepressant with established clinical efficacy, acts as a
melatonin receptor agonist and 5-HT 2C receptor antagonist. As stress is a significant risk
factor in the development of depression, we sought to determine if chronic agomelatine ...

Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators

BS McEwen - European journal of pharmacology, 2008 - Elsevier
... Indeed, there are important differences in the effects of acute and chronic stress, as well as
differences in the consequences of acute ... to disease, we introduced the term “allostatic load or
overload” to refer to the wear and tear that results from either too much stress or from ...

Oxidative stress and diabetic vascular complications.

D Giugliano, A Ceriello, G Paolisso - Diabetes care, 1996 - europepmc.org
... hyperglycemia and the development of secondary complications of diabetes, they have not defined
the mechanism through which excess glucose results in tissue ... In further support of the
consequential injurious role of oxidative stress, many of the adverse effects of high ...

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