Based on the theoretical work of Lincoln and Guba, this practical text is designed to help
new researchers apply the constructivist paradigm. The authors show how these ideas
shape the practice of conducting alternative paradigm research. Covering the research …

Studies of the human microbiome have revealed that even healthy individuals differ
remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of
this diversity remains unexplained, although diet, environment, host genetics and early …

Preliminary classification criteria for the antiphospholipid syndrome (APS) were formulated
during a post-conference workshop held October 10, 1998 in Sapporo, Japan, following the
Eighth International Symposium on Antiphospholipid Antibodies. Members of the workshop …

Background Mentaldisordershavea strong associationwith suicide.Thismeta analysis,or
statisticaloverview, ofthe literature givesanestimateofthe suicide risk ofthe common mental
disorders … Method We searchedthe medical literature to find reports on the mortality ofmental …

The green alga Chlamydomonas is widely used as an experimental model system for
studies in cellular and molecular biology, and in particular plant molecular biology. This
book is the only single modern compendium of information on its biology and in particular its …

Mevinolin, a fungal metabolite, was isolated from cultures of Aspergillus terreus. The
structure and absolute configuration of mevinolini and its open acid form, mevinolinic acid,
were determined by a combination of physical techniques. Mevinolin was shown to be 1, 2 …

Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land
plants over 1 billion years ago. It is a model system for studying chloroplast-based
photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia) …

IN 1947, a technician who had rheumatoid arthritis and who worked in the laboratory of Dr.
Harry Rose at Columbia University discovered that her own serum agglutinated excessively.
Dr. Rose suggested that this serologic reaction might have been caused by the arthritis …

Background Benign prostatic hyperplasia is commonly treated with alpha-adrenergic–
receptor antagonists (alpha-blockers) or 5α-reductase inhibitors. The long-term effect of
these drugs, singly or combined, on the risk of clinical progression is unknown. Methods We …

A new solid-phase radioimmunoassay for the detection of anticardiolipin antibodies is 200-
400 times more sensitive than the precipitation method used in the Venereal Disease
Reference Laboratory test. 61% of serum samples from patients with systemic lupus …