Objective: To determine the cognitive effects of long-term dietary soy isoflavones in a daily
dose comparable to that of traditional Asian diets. Methods: In the double-blind Women's
Isoflavone Soy Health trial, healthy postmenopausal women were randomly allocated to ...

Abstract Cognitive disorders can be associated with brain trauma, neurodegenerative
disease or as a part of physiological aging. Aging in humans is generally associated with
deterioration of cognitive performance and, in particular, learning and memory. Different ...

... on phytoestrogens and cognition. Briefly, this 6-month trial was conducted as a
randomized, double-blind, placebo-controlled, parallel groups study of postmenopausal
women aged 55 to 74 years. Current use of estrogen-containing ...

... Casini ML, Marelli G, Papaleo E et al (2006) Psychological assessment of the effects of
treatment with phytoestrogens on postmenopausal women: a randomized, double-blind,
crossover, placebo-controlled study. Fertil Steril 85:972–978PubMed. 14. ...

... The cognitive performance of postmenopausal women was significantly improved
after the application of soy isoflavones (daily dose of 110 mg) for six months in a
randomized double-blind, placebo-controlled clinical trial [18]. ...

... Each participant first filled out appropriate consent documentation, completed the family medical
history question- naire, and indicated that they had fasted for at least 8 hours prior to the
experiment. ... All participants were blind regarding the type of protein they consumed. ...

... Selection of nerve cells for analysis was random, and all recording and morphological analyses
were conducted blind to the experimental condition. ... Glutamate solution was prepared prior to
each experiment, whereas Aβ 25–35 was dissolved in sterile distilled water at a ...

... METHODS Participants Thirty women aged greater than 60 years who had been postmenopausal
for at least 5 years, had never received hormone replacement therapy and who complained of
memory difficulties, participated in a randomized, double-blind, cross- over study. ...

... J Nutr Health Aging, 2007. 11(2): p. 155-64. 18. Ho, SC, et al., Effects of soy isoflavone
supplementation on cognitive function in Chinese postmenopausal women: a double-blind,
randomized, controlled trial. Menopause, 2007. 14(3 Pt 1): p. 489-99. 19. ...