The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies
V Quintero-Hernández, VR Juárez-González… - Molecular …, 2007 - Elsevier
The antigen-binding fragment (Fab) has been considered a more functionally stable version
of recombinant antibodies than single chain antibody fragments (scFvs), however this
intuitive consideration has not been sufficiently proven in vivo. This communication shows …
of recombinant antibodies than single chain antibody fragments (scFvs), however this
intuitive consideration has not been sufficiently proven in vivo. This communication shows …