Stepwise molding of a highly selective ribonucleopeptide receptor

S Sato, M Fukuda, M Hagihara, Y Tanabe… - Journal of the …, 2005 - ACS Publications
The structural characteristics of RNA− peptide (RNP) complexes are suitable for molding of
a ligand-binding pocket of the RNP complex in a stepwise manner. The first step involves
molding of the RNA subunit by in vitro selection of an RNP pool originating from an RNA …