In vitro selection and evolution of functional proteins by using ribosome display
J Hanes, A Plückthun - … of the National Academy of Sciences, 1997 - National Acad Sciences
We report here a system with which a correctly folded complete protein and its encoding
mRNA both remain attached to the ribosome and can be enriched for the ligand-binding
properties of the native protein. We have selected a single-chain fragment (scFv) of an …
mRNA both remain attached to the ribosome and can be enriched for the ligand-binding
properties of the native protein. We have selected a single-chain fragment (scFv) of an …
