Protective role for interferon-β in coxsackievirus B3 infection

R Deonarain, D Cerullo, K Fuse, PP Liu, EN Fish - Circulation, 2004 - Am Heart Assoc
coxsackievirus infections. Methods and Results— To examine the contribution of IFN-β in
protection from coxsackievirus B3 (… Selection of an attenuated coxsackievirus B3 variant, using …

Cardioselective infection with coxsackievirus B3 requires intact type I interferon signaling: implications for mortality and early viral replication

R Wessely, K Klingel, KU Knowlton, R Kandolf - Circulation, 2001 - Am Heart Assoc
Interferons (IFNs) play an important role in antiviral defense and have therapeutic potential in
coxsackievirus … I and type II IFN signaling in coxsackievirus B3 (CVB3) infection or their role …

Pancreatic expression of interferon-γ protects mice from lethal coxsackievirus B3 infection and subsequent myocarditis

MS Horwitz, A La Cava, C Fine, E Rodriguez, A Ilic… - Nature medicine, 2000 - nature.com
… the coxsackievirus B serogroup as the leading culprit 2,3 . Not only has coxsackievirus B3
(CB3… Transgenic mice expressing interferon-γ in their pancreatic β cells failed to develop CB-3-…

Beta interferon regulation of glucose metabolism is PI3K/Akt dependent and important for antiviral activity against coxsackievirus B3

JD Burke, LC Platanias, EN Fish - Journal of virology, 2014 - Am Soc Microbiol
… ABSTRACT An effective type I interferon (IFN)-mediated … response during infection with
coxsackievirus B3 (CVB3). Last, we … IMPORTANCE Type I interferons (IFN) are critical effectors of …

Protective effect of recombinant alpha interferon on coxsackievirus B3 myocarditis in mice

A Matsumori, N Tomioka, C Kawai - American Heart Journal, 1988 - Elsevier
… Effect of interferon aA/D on coxsackievirus B3 replication in the heart. Virus replication
was inhibited when interferon was administered starting 1 day before or on the day of virus …

Astragaloside IV exerts antiviral effects against coxsackievirus B3 by upregulating interferon

Y Zhang, H Zhu, C Huang, X Cui, Y Gao… - Journal of …, 2006 - journals.lww.com
Coxsackievirus B3 (CVB3) is a major pathogen for viral … Coxsackievirus B3 (CVB3) is one
of the most important … by activating NF-κB, inducing interferon gamma (IFN-γ) expression and …

Coxsackie B3 virus can replicate in cultured human foetal heart cells and is inhibited by interferon

R Kandolf, A Canu, PH Hofschneider - Journal of molecular and cellular …, 1985 - Elsevier
… In order to investigate the relationship between Coxsackie B3 (CB3) virus and human … To
answer the question of whether or not Coxsackie B3 virus can infect cultivated human myocytes…

Antibody-dependent enhancement of coxsackievirus B4 infectivity of human peripheral blood mononuclear cells results in increased interferon-α synthesis

D Hober, W Chehadeh, A Bouzidi… - The Journal of infectious …, 2001 - academic.oup.com
… formed immune complexes with coxsackievirus B4 (CVB4) … infectious particles were
demonstrated when interferon (IFN)–… Coxsackieviruses B1B6 (CVBs) are nonenveloped viruses …

Synergistic interaction of interferon-β and interferon-γ in coxsackievirus B3-infected carrier cultures of human myocardial fibroblasts

A Heim, A Canu, P Kirschner, T Simon… - Journal of Infectious …, 1992 - academic.oup.com
interferon-s (IFN-P) and human recombinant interferon-v (rIFN~'Y) were studied in persistently
coxsackievirus B3-… Picornaviridae, such as the group B coxsackieviruses (CVB, types 1-5), …

Viral protein VP4 is a target of human antibodies enhancing coxsackievirus B4-and B3-induced synthesis of alpha interferon

W Chehadeh, PE Lobert, P Sauter, A Goffard… - Journal of …, 2005 - Am Soc Microbiol
Coxsackievirus B4 (CVB4)-induced production of alpha interferon (IFN- ) by peripheral
blood … and insulin-dependent hyperglycemia in mice infected with coxsackie virus B4. J. Exp. …