Current and experimental treatments of Parkinson disease: A guide for neuroscientists
W Oertel, JB Schulz - Journal of neurochemistry, 2016 - Wiley Online Library
… Over a period of more than 50 years, the symptomatic treatment of the motor symptoms of
Parkinson disease (PD) has been optimized using pharmacotherapy, deep brain stimulation, …
Parkinson disease (PD) has been optimized using pharmacotherapy, deep brain stimulation, …
Regulation of protein kinase C by the anti‐Parkinson drug, MAO‐B inhibitor, rasagiline and its derivatives, in vivo
O Bar‐Am, M Yogev‐Falach, T Amit… - Journal of …, 2004 - Wiley Online Library
… We have recently shown that the anti-Parkinson-propargyl-containing monoamine oxidase
B (MAO-B) inhibitor drug, rasagiline [N-propargyl-(1R)-aminoindan], and its cholinesterase …
B (MAO-B) inhibitor drug, rasagiline [N-propargyl-(1R)-aminoindan], and its cholinesterase …
Symptom relief in Parkinson disease by safinamide: biochemical and clinical evidence of efficacy beyond MAO-B inhibition
F Stocchi, L Vacca, P Grassini, MF De Pandis… - Neurology, 2006 - AAN Enterprises
… as evaluated by the Unified Parkinson Disease Rating Scale (… Because MAO-B was fully
inhibited (95%) at all doses tested, we … MAO-B inhibitor, 6 providing complete platelet MAO-B …
inhibited (95%) at all doses tested, we … MAO-B inhibitor, 6 providing complete platelet MAO-B …
[HTML][HTML] Neuroprotection of MAO-B inhibitor and dopamine agonist in Parkinson disease
P Kong, B Zhang, P Lei, X Kong, S Zhang… - … journal of clinical and …, 2015 - ncbi.nlm.nih.gov
… the MAO-B inhibitor and DA agonist drugs have neuroprotective activity were selected to
explore their neuroprotective effect on Parkinson … agents for the treatment of Parkinson disease. …
explore their neuroprotective effect on Parkinson … agents for the treatment of Parkinson disease. …
[HTML][HTML] G/A polymorphism in intronic sequence affects the processing of MAO-B gene in patients with Parkinson disease
E Jakubauskiene, V Janaviciute, I Peciuliene… - FEBS letters, 2012 - Elsevier
… levels of MAO-B mRNA and enzymatic activity have been reported in platelets from patients
with Parkinson’… The increased MAO-B protein levels might serve as a surrogate marker for – …
with Parkinson’… The increased MAO-B protein levels might serve as a surrogate marker for – …
Gene‐Gene Interaction Between FGF20 and MAOB in Parkinson Disease
… oxidase B (MAOB) genes are associated with Parkinson Disease … MAOB genes for evidence
of interaction contributing to PD risk. Fourteen polymorphisms (eight for FGF20, six for MAOB…
of interaction contributing to PD risk. Fourteen polymorphisms (eight for FGF20, six for MAOB…
Polymorphism in environment responsive genes and association with Parkinson disease
M Singh, AJ Khan, PP Shah, R Shukla… - Molecular and cellular …, 2008 - Springer
… –detoxication and dopaminergic pathways and susceptibility to Parkinson’s disease (PD). …
Significant association was observed for monoamine oxidase-B(MAO-B) variant allele G …
Significant association was observed for monoamine oxidase-B(MAO-B) variant allele G …
Family‐based case–control study of MAOA and MAOB polymorphisms in Parkinson disease
… and MAOB located on the X chromosome, have been considered as possible factors in the
pathogenesis of Parkinson disease (PD). Previous association studies of PD and MAO genes …
pathogenesis of Parkinson disease (PD). Previous association studies of PD and MAO genes …
[PDF][PDF] Managing the patient with newly diagnosed Parkinson disease
C Singer - Cleveland Clinic journal of medicine, 2012 - scholar.archive.org
… ) decline was slower when STN DBS was administered earlier in the course of Parkinson …
Parkinson Study Group. A controlled trial of rotigotine monotherapy in early Parkinson’s …
Parkinson Study Group. A controlled trial of rotigotine monotherapy in early Parkinson’s …
Treatment options in the modern management of Parkinson disease
AHV Schapira - Archives of Neurology, 2007 - jamanetwork.com
… Decision pathway for the treatment of advancing and complex Parkinson disease. MAO-BI
indicates monoamine oxidase B inhibitor; COMT-I, catechol-O-methyltransferase inhibitor. …
indicates monoamine oxidase B inhibitor; COMT-I, catechol-O-methyltransferase inhibitor. …