Nonalcoholic steatohepatitis and the metabolic syndrome
BA Neuschwander-Tetri - The American journal of the medical sciences, 2005 - Elsevier
Relatively recently, the liver has been recognized as a major target of injury in patients with
insulin resistance or the metabolic syndrome. Insulin resistance is associated with fat
accumulation in the liver, a condition called nonalcoholic fatty liver disease (NAFLD). Excess
fat in the liver is not a benign condition. Some patients with NAFLD develop
necroinflammatory changes in the liver called nonalcoholic steatohepatitis (NASH) and a
fraction of those will develop cirrhosis. About 20% all adults have NAFLD and 2% to 3% of …
insulin resistance or the metabolic syndrome. Insulin resistance is associated with fat
accumulation in the liver, a condition called nonalcoholic fatty liver disease (NAFLD). Excess
fat in the liver is not a benign condition. Some patients with NAFLD develop
necroinflammatory changes in the liver called nonalcoholic steatohepatitis (NASH) and a
fraction of those will develop cirrhosis. About 20% all adults have NAFLD and 2% to 3% of …
