The histopathology of acute intestinal amebiasis. A rectal biopsy study.
K Prathap, R Gilman - The American journal of pathology, 1970 - ncbi.nlm.nih.gov
K Prathap, R Gilman
The American journal of pathology, 1970•ncbi.nlm.nih.govMaterials and Methods Fifty-one patients were Orang Asli adults (Western Malaysian
aborigines) admitted to Gombak Hospital with the complaint of passing blood and mucus in
their stools. All of these patients had motile, erythrophagous trophozoites of Entameba
histolytica in stool specimens or proctoscopic aspirate. In addition, positive biopsies from 2
Chinese patients were available for study. Twelve negative rectal biopsies, taken to exclude
amyloidosis in patients without intestinal symptoms, were used as controls. Rectal biopsies …
aborigines) admitted to Gombak Hospital with the complaint of passing blood and mucus in
their stools. All of these patients had motile, erythrophagous trophozoites of Entameba
histolytica in stool specimens or proctoscopic aspirate. In addition, positive biopsies from 2
Chinese patients were available for study. Twelve negative rectal biopsies, taken to exclude
amyloidosis in patients without intestinal symptoms, were used as controls. Rectal biopsies …
Materials and Methods Fifty-one patients were Orang Asli adults (Western Malaysian aborigines) admitted to Gombak Hospital with the complaint of passing blood and mucus in their stools. All of these patients had motile, erythrophagous trophozoites of Entameba histolytica in stool specimens or proctoscopic aspirate. In addition, positive biopsies from 2 Chinese patients were available for study. Twelve negative rectal biopsies, taken to exclude amyloidosis in patients without intestinal symptoms, were used as controls.
Rectal biopsies were done using a Welch-Allyn proctoscope with offset rectal biopsy forceps. The specimens were immediately fixed in 10% formalin and sub-sequently embedded in paraffin. Sections were cut perpendicular to the mucosal surface at 5 R and stained with hematoxylin and eosin, Masson's trichrome, periodic acid-Schiff (PAS), phosphotungstic acid-hematoxylin (PTAH) and, in selected cases, Gordon and Sweet's reticulin stain. In addition to qualitative assessment of tissue changes, an attempt was made to
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