Increased levels of macrophage migration inhibitory factor (MIF) in preeclampsia
T Todros, S Bontempo, E Piccoli, F Ietta… - European Journal of …, 2005 - Elsevier
OBJECTIVE: MIF is a proinflammatory cytokine involved in reproduction. Systemic activation
of maternal inflammatory cell responses may play an important role in the pathogenesis of
preeclampsia (PE). We hypothesized that MIF could be involved in preeclampsia. STUDY
DESIGN: Concentration of immunoreactive MIF was assayed by enzyme-linked
immunoassorbent assay (ELISA) in maternal serum samples obtained from 41 term control
pregnancies and 21 severe preeclamptic pregnancies (14 delivered before and 7 at or after …
of maternal inflammatory cell responses may play an important role in the pathogenesis of
preeclampsia (PE). We hypothesized that MIF could be involved in preeclampsia. STUDY
DESIGN: Concentration of immunoreactive MIF was assayed by enzyme-linked
immunoassorbent assay (ELISA) in maternal serum samples obtained from 41 term control
pregnancies and 21 severe preeclamptic pregnancies (14 delivered before and 7 at or after …
