[PDF][PDF] Effects of suggestion and conditioning on the action of chemical agents in human subjects—the pharmacology of placebos
S Wolf - The Journal of Clinical Investigation, 1950 - Am Soc Clin Investig
S Wolf
The Journal of Clinical Investigation, 1950•Am Soc Clin InvestigMETHOD Initial observations were madeon Tom, a human sub-ject with a large gastric
fistula, in whom itwas possible to observe directly the gastric mucous membrane, cor-
relating changes in color and turgidity with simultaneous measurements of secretion and
motor activity (1). Four other human subjects provided supplementary experimental
opportunities. The methods used in measuring and recording the indicators of gastric
function are described in detail else-where (1). Acid secretion is designated not only in titrat …
fistula, in whom itwas possible to observe directly the gastric mucous membrane, cor-
relating changes in color and turgidity with simultaneous measurements of secretion and
motor activity (1). Four other human subjects provided supplementary experimental
opportunities. The methods used in measuring and recording the indicators of gastric
function are described in detail else-where (1). Acid secretion is designated not only in titrat …
METHOD
Initial observations were madeon Tom, a human sub-ject with a large gastric fistula, in whom itwas possible to observe directly the gastric mucous membrane, cor-relating changes in color and turgidity with simultaneous measurements of secretion and motor activity (1). Four other human subjects provided supplementary experimental opportunities.
The methods used in measuring and recording the indicators of gastric function are described in detail else-where (1). Acid secretion is designated not only in titrat-able units, but also as the quantity of 0.17 N HCl secreted by the stomach per 15 minute collection period. The fig-ure for this quantity is derived from the volume of secre-tion and the total acidity with reference to a formula developed by Hollander (1). Under average circumstances the resting stomach secretion approximates 5 cc. 0.17 N HCO per hour.
The Journal of Clinical Investigation