Long-term food restriction depresses serum thyroid hormone concentrations in the rat
JT Herlihy, C Stacy, HA Bertrand - Mechanisms of ageing and development, 1990 - Elsevier
Long-term food restriction exerts an anti-aging action in rodents. The mechanism underlying
its modulation of aging processes is unknown but changes in endocrine systems have been
postulated as couplers of food restriction to aging. The effects of long-term food restriction on
the serum concentrations of thyroid hormones were examined in 6-month-old, male Fischer
344 rats. For 4.5 months a Food Restricted group was fed 60% of the amount consumed by
an Ad Libitum group. Food restriction did not alter the 24-h mean T 4 concentration but …
its modulation of aging processes is unknown but changes in endocrine systems have been
postulated as couplers of food restriction to aging. The effects of long-term food restriction on
the serum concentrations of thyroid hormones were examined in 6-month-old, male Fischer
344 rats. For 4.5 months a Food Restricted group was fed 60% of the amount consumed by
an Ad Libitum group. Food restriction did not alter the 24-h mean T 4 concentration but …