Aluminum exposure from parenteral nutrition in preterm infants: bone health at 15-year follow-up
MS Fewtrell, NJ Bishop, CJ Edmonds, EB Isaacs… - Pediatrics, 2009 - Am Acad Pediatrics
OBJECTIVE: Aluminum has known neurotoxicity and may impair short-term bone health. In a
randomized trial, we showed reduced neurodevelopmental scores in preterm infants who
were previously exposed to aluminum from parenteral nutrition solutions. Here, in the same
cohort, we test the hypothesis that neonatal aluminum exposure also adversely affects long-
term bone health, as indicated by reduced bone mass. METHODS: Bone area (BA) and
bone mineral content (BMC) of lumbar spine, hip, and whole body were measured with dual …
randomized trial, we showed reduced neurodevelopmental scores in preterm infants who
were previously exposed to aluminum from parenteral nutrition solutions. Here, in the same
cohort, we test the hypothesis that neonatal aluminum exposure also adversely affects long-
term bone health, as indicated by reduced bone mass. METHODS: Bone area (BA) and
bone mineral content (BMC) of lumbar spine, hip, and whole body were measured with dual …