Assessment of mammalian embryo quality: what can we learn from embryo morphology?

A Van Soom, B Mateusen, J Leroy, A De Kruif - Reproductive biomedicine …, 2003 - Elsevier
Embryo morphology assessment, however imperfect it may be, is at present the most
popular method for embryo selection prior to transfer, both in human and bovine assisted
reproduction. A major difference between human and bovine embryos is the fact that in the
latter, assessment of morphology is jeopardized by the opacity of the blastomeres, which is
caused by lipid droplet accumulation. This opacity makes it difficult to assess nuclear and
nucleolar morphology, aspects which can easily be evaluated in human zygotes or early …