Brain grey matter volume alterations in late-life depression
M Du, J Liu, Z Chen, X Huang, J Li, W Kuang… - Journal of Psychiatry and …, 2014 - jpn.ca
Background: Voxel-based morphometry (VBM) studies have demonstrated that grey matter
abnormalities are involved in the pathophysiology of late-life depression (LLD), but the
findings are inconsistent and have not been quantitatively reviewed. The aim of the present
study was to conduct a meta-analysis that integrated the reported VBM studies, to determine
consistent grey matter alterations in individuals with LLD. Methods: A systematic search was
conducted to identify VBM studies that compared patients with LLD and healthy controls. We …
abnormalities are involved in the pathophysiology of late-life depression (LLD), but the
findings are inconsistent and have not been quantitatively reviewed. The aim of the present
study was to conduct a meta-analysis that integrated the reported VBM studies, to determine
consistent grey matter alterations in individuals with LLD. Methods: A systematic search was
conducted to identify VBM studies that compared patients with LLD and healthy controls. We …
