Controlling the false discovery rate: a practical and powerful approach to multiple testing
Y Benjamini, Y Hochberg - Journal of the royal statistical society. Series B …, 1995 - JSTOR
The common approach to the multiplicity problem calls for controlling the familywise error
rate (FWER). This approach, though, has faults, and we point out a few. A different approach
to problems of multiple significance testing is presented. It calls for controlling the expected
proportion of falsely rejected hypotheses-the false discovery rate. This error rate is
equivalent to the FWER when all hypotheses are true but is smaller otherwise. Therefore, in
problems where the control of the false discovery rate rather than that of the FWER is …
rate (FWER). This approach, though, has faults, and we point out a few. A different approach
to problems of multiple significance testing is presented. It calls for controlling the expected
proportion of falsely rejected hypotheses-the false discovery rate. This error rate is
equivalent to the FWER when all hypotheses are true but is smaller otherwise. Therefore, in
problems where the control of the false discovery rate rather than that of the FWER is …
