[HTML][HTML] Critical appraisal skills are essential to informed decision-making

R Mhaskar, P Emmanuel, S Mishra, S Patel… - Indian journal of …, 2009 - ncbi.nlm.nih.gov
Whenever a trial is conducted, there are three possible explanations for the results: a)
findings are correct (truth), b) represents random variation (chance) or c) they are influenced
by systematic error (bias). Random error is deviation from the 'truth'and happens due to play
of chance (eg trials with small sample, etc.). Systematic distortion of the estimated
intervention effect away from the 'truth'can also be caused by inadequacies in the design,
conduct or analysis of a trial. Several studies have shown that bias can obscure up to 60% of …