Dose-response study of N, N-dimethyltryptamine in humans: II. Subjective effects and preliminary results of a new rating scale
RJ Strassman, CR Qualls, EH Uhlenhuth… - Archives of general …, 1994 - jamanetwork.com
Background: Validation of animal models of hallucinogenic drugs' subjective effects requires
human data. Previous human studies used varied groups of subjects and assessment
methods. Rating scales for hallucinogen effects emphasized psychodynamic principles or
the drugs' dysphoric properties. We describe the subjective effects of graded doses of N, N-
dimethyltryptamine (DMT), an endogenous hallucinogen and drug of abuse, in a group of
experienced hallucinogen users. We also present preliminary data from a new rating scale …
human data. Previous human studies used varied groups of subjects and assessment
methods. Rating scales for hallucinogen effects emphasized psychodynamic principles or
the drugs' dysphoric properties. We describe the subjective effects of graded doses of N, N-
dimethyltryptamine (DMT), an endogenous hallucinogen and drug of abuse, in a group of
experienced hallucinogen users. We also present preliminary data from a new rating scale …
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