Effects of β-carboline harmine on behavioral and physiological parameters observed in the chronic mild stress model: Further evidence of antidepressant properties
JJ Fortunato, GZ Réus, TR Kirsch, RB Stringari… - Brain research …, 2010 - Elsevier
The chronic mild stress (CMS) model has been used as an animal model of depression
which induces anhedonic behavior in rodents. The present study was aimed to evaluate the
behavioral and physiological effects of administration of β-carboline harmine in rats exposed
to CMS procedure. To this aim, after 40 days of exposure to CMS procedure, rats were
treated with harmine (15mg/kg/day) for 7 days. In this study, sweet food consumption,
adrenal gland weight, adrenocorticotrophin hormone (ACTH) levels, and hippocampal brain …
which induces anhedonic behavior in rodents. The present study was aimed to evaluate the
behavioral and physiological effects of administration of β-carboline harmine in rats exposed
to CMS procedure. To this aim, after 40 days of exposure to CMS procedure, rats were
treated with harmine (15mg/kg/day) for 7 days. In this study, sweet food consumption,
adrenal gland weight, adrenocorticotrophin hormone (ACTH) levels, and hippocampal brain …
