Evidence for episodic but not circadian activity in plasma concentrations of adrenocorticotrophin, cortisol and thyroxine in dogs
RJ Kemppainen, JL Sartin - Journal of Endocrinology, 1984 - Soc Endocrinology
Concentrations of immunoreactive (i) ACTH, cortisol and thyroxine were determined in
plasma samples obtained at 20-min intervals for 25 h in nine normal and two
adrenalectomized dogs. The dogs were exposed to a 12 h light: 12 h darkness photoperiod
for 30 days before the sampling period. Episodic secretion of iACTH and cortisol was
evident in each normal dog, with an average of 9· 0 iACTH peaks and 10· 1 cortisol peaks in
a 24-h period. Levels of iACTH and cortisol were significantly correlated in each normal dog …
plasma samples obtained at 20-min intervals for 25 h in nine normal and two
adrenalectomized dogs. The dogs were exposed to a 12 h light: 12 h darkness photoperiod
for 30 days before the sampling period. Episodic secretion of iACTH and cortisol was
evident in each normal dog, with an average of 9· 0 iACTH peaks and 10· 1 cortisol peaks in
a 24-h period. Levels of iACTH and cortisol were significantly correlated in each normal dog …
