Methods and tools in genome-wide association studies

AC Gumpinger, D Roqueiro, DG Grimm… - Computational Cell …, 2018 - Springer
Many traits, such as height, the response to a given drug, or the susceptibility to certain
diseases are presumably co-determined by genetics. Especially in the field of medicine, it is
of major interest to identify genetic aberrations that alter an individual's risk to develop a
certain phenotypic trait. Addressing this question requires the availability of comprehensive,
high-quality genetic datasets. The technological advancements and the decreasing cost of
genotyping in the last decade led to an increase in such datasets. Parallel to and in line with …