Abstract N, N-dimethyltryptamine (DMT) is an indole alkaloid widely found in plants and
animals. It is best known for producing brief and intense psychedelic effects when ingested.
Increasing evidence suggests that endogenous DMT plays important roles for a number of
processes in the periphery and central nervous system, and may act as a neurotransmitter.
This paper reviews the current literature of both the recreational use of DMT and its potential
roles as an endogenous neurotransmitter. Pharmacokinetics, mechanisms of action in the …