On the adaptive control of the false discovery rate in multiple testing with independent statistics
Y Benjamini, Y Hochberg - Journal of educational and …, 2000 - journals.sagepub.com
A new approach to problems of multiple significance testing was presented in Benjamini and
Hochberg (1995), which calls for controlling the expected ratio of the number of erroneous
rejections to the number of rejections–the False Discovery Rate (FDR). The procedure given
there was shown to control the FDR for independent test statistics. When some of the
hypotheses are in fact false, that procedure is too conservative. We present here an adaptive
procedure, where the number of true null hypotheses is estimated first as in Hochberg and …
Hochberg (1995), which calls for controlling the expected ratio of the number of erroneous
rejections to the number of rejections–the False Discovery Rate (FDR). The procedure given
there was shown to control the FDR for independent test statistics. When some of the
hypotheses are in fact false, that procedure is too conservative. We present here an adaptive
procedure, where the number of true null hypotheses is estimated first as in Hochberg and …
