Regular motor activity has many benefits for mental and physical condition but its
implications for epilepsy are still controversial. In order to elucidate this problem, we have
studied the effect of long-term physical activity on susceptibility to subsequent seizures. Male
Wistar rats were subjected to repeated training sessions in a treadmill and swimming pool.
Thereafter, seizures were induced by pilocarpine injections in trained and non-trained
control groups. During the acute period of status epilepticus, we measured:(1) the latency of …