Context Previous studies indicate that the interpretation of trial results can be distorted by
authors of published reports. Objective To identify the nature and frequency of distorted
presentation or “spin”(ie, specific reporting strategies, whatever their motive, to highlight that
the experimental treatment is beneficial, despite a statistically nonsignificant difference for
the primary outcome, or to distract the reader from statistically nonsignificant results) in
published reports of randomized controlled trials (RCTs) with statistically nonsignificant …