Stress‐induced alterations in metabolism of γ‐aminobutyric acid in rat brain
Y Yoneda, K Kanmori, S Ida… - Journal of …, 1983 - Wiley Online Library
The effect of a stressful manipulation on the metabolism of γ‐aminobutyric acid (GABA) in
the rat brain was studied. Application of an immobilized stress to animals induced a
significant increase in the striatal and hypothalamic GABA contents without affecting those in
other central structures examined. It was also found that the increase in striatal GABA level
preceded that in the hypothalamus. This increase in steady‐state levels of GABA in the
striatum and hypothalamus disappeared at 12 h after the termination of the application of …
the rat brain was studied. Application of an immobilized stress to animals induced a
significant increase in the striatal and hypothalamic GABA contents without affecting those in
other central structures examined. It was also found that the increase in striatal GABA level
preceded that in the hypothalamus. This increase in steady‐state levels of GABA in the
striatum and hypothalamus disappeared at 12 h after the termination of the application of …
