Swimming training prevents pentylenetetrazol‐induced inhibition of Na+, K+‐ATPase activity, seizures, and oxidative stress
Purpose: In the present study we decided to investigate whether physical exercise protects
against the electrographic, oxidative, and neurochemical alterations induced by
subthreshold to severe convulsive doses of pentyltetrazole (PTZ). Methods: The effect of
swimming training (6 weeks) on convulsive behavior induced by PTZ (30, 45, and 60 mg/kg,
ip) was measured and different electrographic electroencephalography (EEG) frequencies
obtained from freely moving rats. After EEG recordings, reactive oxygen species (ROS) …
against the electrographic, oxidative, and neurochemical alterations induced by
subthreshold to severe convulsive doses of pentyltetrazole (PTZ). Methods: The effect of
swimming training (6 weeks) on convulsive behavior induced by PTZ (30, 45, and 60 mg/kg,
ip) was measured and different electrographic electroencephalography (EEG) frequencies
obtained from freely moving rats. After EEG recordings, reactive oxygen species (ROS) …