Systemic adaptation to oxidative challenge induced by regular exercise

Z Radak, HY Chung, S Goto - Free Radical Biology and Medicine, 2008 - Elsevier
Exercise is associated with increased ATP need and an enhanced aerobic and/or anaerobic
metabolism, which results in an increased formation of reactive oxygen species (ROS).
Regular exercise seems to decrease the incidence of a wide range of ROS-associated
diseases, including heart disease, type II diabetes, rheumatic arthritis, Alzheimer and
Parkinson diseases, and certain cancers. The preventive effect of regular exercise, at least
in part, is due to oxidative stress-induced adaptation. The oxidative challenge-related …